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Benzodiazepines like diazepam are lipophilic and promptly penetrate membranes, so swiftly cross above in the placenta with sizeable uptake with the drug. Usage of benzodiazepines together with diazepam in late pregnancy, Specially large doses, can result in floppy infant syndrome.[62] Diazepam when taken late in pregnancy, during the third trimeste

Advise the two people and caregivers in regards to the dangers of respiratory depression and sedation when diazepam is made use of with opioids. Recommend patients not to drive or operate heavy machinery right until the consequences of concomitant use With all the opioid are already determined (see Safety measures: DRUG INTERACTIONS).For more info